Antigen persists in discrete cell populations within the lymph
node
Experimental design
Mean Ag-score is shown for each cell type for 2, 14, 21, and 42 days
post vaccination.
UMAP projection shows LEC subsets.
UMAP projections show Ag-scores for LEC subsets for each
timepoint.
Mean Ag-score is shown for LEC subsets for each timepoint.
Ag-scores are shown for each timepoint for each LEC subset.
UMAP projection shows DC subsets.
UMAP projections show Ag-scores for DC subsets for each
timepoint.
Mean Ag-score is shown for DC subsets for each timepoint.
Ag-scores are shown for each timepoint for each DC subset.
Notes
Only experiment 1 is shown for the LEC 21 and 42 day timepoints
(including for the UMAPs). Experiment 2 data include very few LECs for
the 21 day timepoint.
Experiment 2 is shown for the DC 21 and 42 day timepoints.
Experiment 1 data are lower quality (sparse signal, mostly zeros).
Subsets are only shown if there are >= 5 cells for each
timepoint
CD45+ and CD45- cell types are only shown for the CD45+ and CD45-
datasets, respectively.
Figure S1
UMAP projections show cell types identified for CD45- and CD45+
samples.
UMAP projections show LEC subsets identified for each
timepoint.
UMAP projections show DC subsets identified for each timepoint.
The expression of key marker genes is shown for LEC subsets.
The expression of key marker genes is shown for DC subsets.